Federal Approach to AI Infrastructure and the Workforce

Many discussions about infrastructure in federal technology center around physical infrastructure — the hardware, software and, of course, the personnel necessary to maintaining and managing all IT operations. But for artificial intelligence, discussions pivot to include more theory and soft skills. This Deep Dive features discussions from federal leaders on the backbones that make up a federal agency’s approach to AI.
Download this Deep Dive to learn more about:
- Ethical AI and the Department of Health and Human Services’ new trustworthy AI framework.
- Key steps leaders at HHS, NASA and the Defense Department are taking to implement AI.
- How data management and interoperability enable AI to succeed.

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Maj. Andrew Armstrong Chief of Data Integration, Kessel Run, U.S. Air Force
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Qi Duan Program Director, Division of Health Informatics Technologies, NIH
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Rafael Fricks Lead AI tech sprints coordinator, VA
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Diana Gehlhaus Research Fellow, Center for Security and Emerging Technology, Georgetown University
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Pamela Isom Director, Artificial Intelligence and Technology Office, U.S. Department of Energy
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Dr. Amy Justice Public Health Professor, Yale University; Leading Clinical Epidemiologist, VA
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Laura Kurup Chief Data & Analytics Officer, Federal Reserve Bank of New York
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Oki Mek Chief AI Officer, U.S. Department of Health & Human Services
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Brett Vaughn Chief AI Officer, U.S. Navy
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Jonathan Weiner Co-Director, Johns Hopkins Center for Population Health IT
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David Womble AI Program Director, Oak Ridge National Laboratory
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Michael Sellitto Human-Centered AI Deputy Director, Stanford University
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AI Foundations Driving Government Efficiency
Federal agencies are modernizing systems, managing risk and building trust to scale responsible AI and drive government efficiency.
40m watch -
Navy Memo Maps Tech Priorities for the Future Fight
Acting CTO’s memo outlines critical investment areas, from AI and quantum to cyber and space, as part of an accelerated modernization push.
5m read -
DOD Can No Longer Assume Superiority in Digital Warfare, Officials Warn
The DOD must make concerted efforts to address cyber vulnerabilities to maintain the tactical edge, military leaders said at HammerCon 2025.
4m read -
New NSF Program Cultivates the Future of NextG Networks
The agency’s new VINES program looks to tackle key challenges like energy efficiency and future-proofing wireless tech.
21m watch -
DHA CDAO Spearheads Master Data Catalog to Boost Transparency
Jesus Caban plans to boost DHA's data maturity through a new master data catalog, governance frameworks and inventory of tech tools.
5m read -
Trump Orders Spark Government-Wide Acquisition Overhaul
As Trump pushes for a faster, simpler procurement system, agencies are leveraging AI and adapting strategies to meet new requirements.
5m read -
Inside Oak Ridge National Lab’s Pioneer Approach to AI
Energy Department’s Oak Ridge National Lab transforms AI vulnerabilities into strategic opportunities for national defense.
22m listen -
A Look at Federal Zero Trust Transformation
Recent developments from CISA and DOD show how government is advancing zero trust quickly.
20m read -
Modernization Strategies to Enable Energy Innovation
Lawrence Berkeley National Lab and Maximus experts explore the modernization strategies driving digital transformation and operational resilience within the energy sector.
33m watch -
DOI Must Modernize Energy to Win AI Race, Secretary Says
Doug Burgum links AI innovation to energy reform as DOI advances digital infrastructure and wildfire response under Trump’s tech agenda.
2m read -
NIST to Release New AI Cybersecurity Guidance as Federal Use Expands
NIST plans to release AI cybersecurity guidance within the year to support safe adoption as federal agencies expand use cases.
4m read -
Federal Zero Trust Forum
The Federal Zero Trust Forum brings together key technology leaders from across government to explore practical strategies and share lessons for advancing zero trust architecture.
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